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1. 发明专利

JP2009091371A Method of application of wrinkle-stretch bonding sheet, and wrinkle-stretch bonding sheet 有权
标题翻译：皱纹粘合片的应用方法和缠绕粘合片
公开(公告)号：JP2009091371A
公开(公告)日：2009-04-30
申请号：JP2009007313
申请日：2009-01-16
申请人： Lintec Corp , リンテック株式会社
发明人： MATSUSHIMA MASARU , OKABE HIDEAKI
IPC分类号： A61K8/81 , A61K8/02 , A61Q19/00 , C09J7/02 , C09J11/06 , C09J131/04 , C09J133/02 , C09J139/06
摘要： PROBLEM TO BE SOLVED: To provide a method of application of a wrinkle-stretch bonding sheet in which bonding and fixation on the skin are ensured, and the wrinkle-stretch effect is high, and to provide the wrinkle-stretch bonding sheet.
SOLUTION: The method of application of the wrinkle-stretch bonding sheet is a method of application of the wrinkle-stretch bonding sheet which comprises laminating a base material layer having air permeability and flexibility and an adhesive layer including a polymeric material having water solubility or water swellability, wherein the adhesive layer has the complex modulus of 5×10
6 -5×10
9 dyne/cm
2 at the strain of 0.1% at the temperature of 35°C and the frequency of 1 Hz; and the adhesive layer is soaked by water, lotion or serum, thereby the self-adhesive property is generated, the adhesive layer is adhered to the skin while the wrinkle of the skin is stretched, the predetermined time of the status that the adhesive layer is adhered and fixed to the skin is continued, thereafter the wrinkle stretch bonding sheet is wetted with water, and removed from the skin.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种皱纹拉伸粘合片的应用方法，其中确保了皮肤上的粘结和固定，并且皱纹拉伸效果高，并且提供皱纹拉伸粘合片。解决方案：皱纹拉伸粘合片的施用方法是应用皱纹拉伸粘合片的方法，其包括层叠具有透气性和柔性的基材层和包含具有水的聚合物的粘合剂层溶解度或水溶胀性，其中粘合剂层的复数模量为5×10 -6 /秒> 5×10 9 /秒> dyne / cm 2 在35℃的温度和1Hz的频率下的应变为0.1％; 并且粘合剂层被水，洗剂或血清浸泡，从而产生自粘性，粘合层粘附到皮肤上，同时使皮肤的皱纹被拉伸，粘合剂层的状态的预定时间粘附并固定在皮肤上，然后将皱纹拉伸粘合片用水润湿，并从皮肤上除去。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2006213603A Adhesive composition for pasting on skin and adhesive sheet for pasting on skin 有权
标题翻译：用于粘贴皮肤和粘合片的粘合剂组合物
公开(公告)号：JP2006213603A
公开(公告)日：2006-08-17
申请号：JP2005025287
申请日：2005-02-01
申请人： Lintec Corp , リンテック株式会社
发明人： TAKANASHI TAKAYA , HOSHI MASARU , OKABE HIDEAKI
IPC分类号： A61K9/70 , A61F13/02 , A61K47/32 , C09J7/02 , C09J133/06 , C09J175/04
摘要： PROBLEM TO BE SOLVED: To provide an adhesive composition for pasting on a skin while maintaining prescribed cohesive force, capable of obtaining the adhesive having high wettability or followability against the skin, and an adhesive sheet for pasting to the skin, equipped with such an adhesive layer.
SOLUTION: This adhesive sheet for pasting on the skin consisting of a supporting body and the adhesive layer laminated on the back side of the supporting material is provided by constituting the adhesive layer by an adhesive obtained by cross-linking the adhesive composition obtained by adding (B) a long chain isocyanate-based cross-linking agent having ≥2 isocyanate groups in its molecule to (A) an adhesive component containing (a) a (meth)acrylic acid ester copolymer having a cross-linkable functional group, (b) a (meth)acrylic oligomer and (c) a (meth)acrylic polymer without having the cross-linkable functional group if desired.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种粘合剂组合物，用于在保持规定的内聚力的同时保持规定的内聚力，能够获得具有高润湿性或对皮肤的追随性的粘合剂，以及粘贴到皮肤上的粘合片，这样的粘合剂层。解决方案：通过将获得的粘合剂组合物交联而获得的粘合剂构成粘合剂层来提供粘合在由支撑体构成的皮肤上的粘合片和层叠在支撑材料的背面上的粘合剂层通过在（A）含有（a）具有可交联官能团的（甲基）丙烯酸酯共聚物的粘合剂组分中加入（B）分子中具有≥2个异氰酸酯基团的长链异氰酸酯基交联剂（B）（b）（甲基）丙烯酸低聚物和（c）如果需要，不具有可交联官能团的（甲基）丙烯酸聚合物。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2005283304A Probe array 审中-公开
标题翻译：探索阵列
公开(公告)号：JP2005283304A
公开(公告)日：2005-10-13
申请号：JP2004097228
申请日：2004-03-29
申请人： Lintec Corp , リンテック株式会社
发明人： YAMAMOTO HIROKO , OKABE HIDEAKI , SAITO RUI
IPC分类号： G01N33/53 , B01J19/00 , C12M1/00 , C12M1/34 , C40B40/06 , C40B60/14 , G01N37/00
CPC分类号： B01J19/0046 , B01J2219/00387 , B01J2219/00475 , B01J2219/00511 , B01J2219/00538 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00662 , B01J2219/00677 , B01J2219/00722 , B82Y30/00 , C40B40/06 , C40B60/14
摘要： PROBLEM TO BE SOLVED: To provide a probe array capable of detecting a target substance with satisfactory reproducibility with simple operation.
SOLUTION: In this probe array provided with the first cylindrical member 11, the second cylindrical member 12 stored in a hollow part of the first member 11, and a probe fixed on an outer circumferential face of the second member 12, a spacer part 13a is provided on the outer circumferential face of the second member 12, so as to prevent an inner circumferential face of the first member 11 from contacting with the outer circumferential face of the second member 12.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供能够以简单的操作以令人满意的再现性检测目标物质的探针阵列。解决方案：在设置有第一圆柱形构件11的探针阵列中，存储在第一构件11的中空部分中的第二圆柱形构件12和固定在第二构件12的外周面上的探针，间隔件部分13a设置在第二构件12的外周面上，以防止第一构件11的内周面与第二构件12的外圆周面接触。版权所有（C）2006 ，JPO＆NCIPI

4. 发明专利

JP2651616B2 失效
公开(公告)号：JP2651616B2
公开(公告)日：1997-09-10
申请号：JP2632289
申请日：1989-02-03
申请人： RINTETSUKU KK
发明人： NAGAI TSUNEJI , TAKAYAMA KOZO , OKABE HIDEAKI
IPC分类号： A61K47/06

5. 发明专利

JPH09176049A GEL PREPARATION COMPOSITION AND GEL PREPARATION 失效
公开(公告)号：JPH09176049A
公开(公告)日：1997-07-08
申请号：JP29962496
申请日：1996-10-24
申请人： LINTEC CORP
发明人： SUZUKI EIJI , OKABE HIDEAKI , KOGURE MASAO , SAITO TAKANORI
IPC分类号： A61K9/06 , A61K9/70 , A61K31/165 , A61K31/167 , A61K31/40 , A61K31/415 , A61K31/455 , A61K31/565 , A61K31/57 , A61K47/32
摘要： PROBLEM TO BE SOLVED: To obtain a gel preparation composition which contains a hydrophilic copolymer of a specific structure, a polyhydric alcohol and a physiologically active substance and is prepared by crosslinking its hydrophilic copolymer, thus manifests excellent transdermal absorption. SOLUTION: This composition contains (A) a hydrophilic copolymer comprising (i) 10-90wt.% of a monomer unit bearing a carboxyl group, preferably (meth) acrylic acid and (ii) 90-10wt.% of other copolymerizable monomers, (B) a polyhydric alcohol and (C) a pharmacologically active substance, preferably at least one selected from progesterone, estradiol, testosterone, pindolol, clonidine, lidocaine and nifedipine and the component A is crosslinked. This composition is laminated to give a gel preparation. The amount of the component B is preferably 50-500 pts.wt., more preferably 100-400 pts.wt. per 100 pts.wt. of the component A, while the component C is preferably 5-100 pts.wt., more preferably 20-70 pts.wt.

6. 发明专利

JPH08216348A ANTIBACTERIAL BASE MATERIAL AND ANTIBACTERIAL ADHESIVE BASE MATERIAL 失效
公开(公告)号：JPH08216348A
公开(公告)日：1996-08-27
申请号：JP5330395
申请日：1995-02-17
申请人： LINTEC CORP
发明人： OKABE HIDEAKI , SUZUKI EIJI , SUGIZAKI TOSHIO , KOGURE MASAO , SAITO TAKANORI
IPC分类号： B32B7/06 , B32B27/18 , C09J7/02
摘要： PURPOSE: To maintain excellent antibacterial force for a long time and easily give antibacterial function to various materials to be attached, by setting a thickness of an antibacterial resin layer of an antibacterial base material provided at least on one face of a base body to a specified magnification or lower of an average grain diameter of an inorganic antibacterial agent. CONSTITUTION: An antibacterial base material has, at least on one face of a base body 3, an antibacterial resin layer 2 consisting of an inorganic antibacterial agent 1 and a resin. The thickness of the resin layer 2 is set to three times or lower of an average grain diameter of the inorganic antibacterial agent. Here, by restraining a using quantity of the resin for binding the antibacterial agent 1, the quantity of the antibacterial agent 1 exposed to the surface of the resin layer is increased. That is, for the thickness of the resin layer 2, three times or lower of the average grain diameter of the antibacterial agent 1 suffices. From the viewpoint of heightening antibacterial efficiency, the thinner the thickness of the resin layer 2 is, the better it is. When the thickness of the resin layer 2 becomes three times or higher of the average grain diameter of the antibacterial agent 1, antibacterial force stays in the same degree as that of a conventional kneading type antibacterial base material.

7. 发明专利

JPH07286914A TEMPERATURE CONTROL LABEL 失效
公开(公告)号：JPH07286914A
公开(公告)日：1995-10-31
申请号：JP10147794
申请日：1994-04-15
申请人： LINTEC CORP , KIROKU SOZAI SOGO KENKYUSHO KK
发明人： SUGIZAKI TOSHIO , OKABE HIDEAKI , KOGURE MASAO , SAITO TAKANORI
IPC分类号： B42D15/00 , G01K11/12
摘要： PURPOSE:To easily and surely determine whether or not the storage temperature of an article has risen above a predetermined temperature by bonding first and second labeling sheets together using a porous sheet, and containing a temperature controlling agent in one or more of the sheets. CONSTITUTION:A first labeling sheet has an adhesive layer which is provided on one side of a base sheet made preferably of a vinyl chloride resin and the like and which contains an organic chelate coupler. A second labeling sheet has an adhesive layer which is provided on one side of a base sheet and which contains a metallic compound that is colored when reacted with the organic chelate coupler, and both adhesive layers are bonded together by a porous sheet and at least one of the sheets contains a temperature controlling agent such as n-paraffin. As the temperature controlling agent flows within the porous sheet in a melting temperature range, either the metallic compound or the organic chelate coupler migrates within the porous sheet and is colored by reaction between them on contact. The color does not disappear even with the sheet kept below the melting point, and is detected to easily and surely determine whether or not the storage temperature of an article has risen above a predetermined temperature.

8. 发明专利

JPH0679267A OIL-ABSORBING SHEET 失效
公开(公告)号：JPH0679267A
公开(公告)日：1994-03-22
申请号：JP23832192
申请日：1992-09-07
申请人： LINTEC CORP
发明人： NAGASHIMA KOSAKU , OKABE HIDEAKI , SAKURAI KUNITOSHI , SAKAI SEI
IPC分类号： B01D15/00 , C02F1/40
摘要： PURPOSE:To provide an oil absorbing sheet which efficiently absorbs oil, has excellent oil holding property without causing dropping of oil, can easily adsorb the oil content suspending in water, and can easily be handled, by constituting the sheet of sheet-type hydrophilic porous base material and an oil absorbent fixed to at least one part of the hydrophilic porous base material. CONSTITUTION:This oil-absorbing sheet has a sandwich structure essentially consisting of two layers of hydrophilic porous base material 1 and granular or powdery oil absorbent 2 interposed between these layers. The oil absorbent 2 is fixed to the hydrophilic porous base material 1 with a binder 3. Thereby, the sheet has such an oil absorbing effect that an oil content absorbed and deposited in the space of fibers of the hydrophilic porous base material 1 is further absorbed by the oil absorbent 2. Namely, the oil content absorbed by the porous base material 1 is further absorbed by the oil absorbent, so that the sheet has excellent oil holding property. Moreover, since the hydrophilic porous base material 1 is used, the oil content once absorbed by the porous base material 1 is efficiently transferred to the oil absorbent 2, and thereby, the oil-absorbing sheet has a dry surface with little tacky state due to the oil content.

9. 发明专利

JPH0579644B2 失效
公开(公告)号：JPH0579644B2
公开(公告)日：1993-11-04
申请号：JP24948589
申请日：1989-09-26
申请人： KOGYO GIJUTSUIN , LINTEC CORP
发明人： GAMA YASUO , ISHIGAMI YUTAKA , OKABE HIDEAKI , KAMAGAMI SABURO , KAIZE HISAYASU
IPC分类号： A61K8/11 , A61K8/00 , A61K8/14 , A61K8/44 , A61K8/49 , A61K9/127 , A61K47/18 , A61Q13/00 , B01J13/02

10. 发明专利

JPH05132418A PRODUCTION OF VOLATILE CARRIER 失效
公开(公告)号：JPH05132418A
公开(公告)日：1993-05-28
申请号：JP32100491
申请日：1991-11-08
申请人： LINTEC CORP
发明人： OKABE HIDEAKI , KATO KAZUYA , NAGAKI HIROSHI
IPC分类号： A61K9/70 , C09J7/02 , C09J133/06 , C09J199/00
摘要： PURPOSE:To obtain a volatile carrier by forming a tacky layer consisting of a volatile agent and a tacky agent having high affinity and impregnating the volatile agent into the tacky agent. CONSTITUTION:A tacky layer consisting of a volatile agent which is a percutaneous absorption promoter such as D-limonene and a tacky agent (e.g. n-butyl (meth)acrylate) of an acrylic polymer having high affinity is formed. Then the volatile agent is impregnated into the tacky layer by a method such as gravure coating or Mayer bar coating and supported on the tacky layer. A sufficiently purified oil can be supported on a shape such as sheetlike shape or labeled shape so that in the production of percutaneous absorption preparation, a volatile medicine, a volatile percutaneous absorption promoter, a volatile additive, etc., can be efficiently contained in high concentrations.

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